Guide
What does TB-500 stand for?
TB-500 is named for thymosin beta-4. What the TB and the 500 mean, what TB-500 costs in Canada, and how to check a vial is the real molecule.
Published October 5, 2026
TB-500 is named for thymosin beta-4: the "TB" stands for thymosin beta, and the "500" is part of the product name with no chemical meaning. Thymosin beta-4 is a natural 43-residue peptide, and TB-500 is a synthetic version of its active region, supplied in acetylated form. You will often see it written TB4 for short, which is why our catalog lists it as TB-500 (TB4).
| Peptide | Vial sizes | From |
|---|---|---|
| TB-500 (TB4) | 5mg, 10mg | $34.99 CAD |
| TB-500 Frag 17-23 | Single size | $59.99 CAD |
| BPC157 + TB500 Blend | 5mg + 5mg, 10mg + 10mg | $64.99 CAD |
Free shipping across Canada. Every vial ships with a QR code linking to its own batch lab report. See all peptides
What the letters and the number in TB-500 mean
The name has two parts, and only one of them tells you anything about the molecule.
- TB is thymosin beta, from thymosin beta-4. That protein binds G-actin and controls how actin filaments form, which is why it turns up in cell-migration and tissue research models.
- 500 is part of the product name. None of TB-500's measurable numbers is 500, as the table shows.
| Number you might expect "500" to be | What it really is for TB-500 |
|---|---|
| Residue count | Thymosin beta-4 has 43 residues |
| Molecular weight | 4963.44 g/mol |
| Formula | C212H350N56O78S |
| CAS number | 77591-33-4 |
| Vial size | 5 mg or 10 mg |
The number that matters on a lab report is the mass. An observed mass near 4963.44 confirms the vial holds TB-500. The full identity sheet and concentration table are in the TB-500 handling guide.
TB-500, TB4 and the fragment are three different labels
Three names get mixed up in search results and on supplier sites:
- Thymosin beta-4 (TB4): the natural 43-residue peptide.
- TB-500: the synthetic version of its active region, 4963.44 g/mol.
- TB-500 fragment 17-23: the seven-residue actin-binding stretch, LKKTETQ, at 729.83 g/mol.
The fragment is about a seventh the mass of TB-500, so a mass-spec line cannot confuse the two. TB-500 vs TB-500 fragment 17-23 explains why it is studied on its own. TB-500 is also often paired with BPC-157, a different molecule entirely, and BPC-157 vs TB-500 sets the two side by side.
What does TB-500 cost in Canada?
pepuro prices TB-500 in Canadian dollars, and shipping inside Canada is free, so the shelf price is the delivered price.
| Product | Vial | Price |
|---|---|---|
| TB-500 | 5 mg | $34.99 |
| TB-500 | 10 mg | $59.99 |
| TB-500 fragment 17-23 | Single size | $59.99 |
| BPC-157 + TB-500 blend | 5 mg + 5 mg | $64.99 |
| BPC-157 + TB-500 blend | 10 mg + 10 mg | $74.99 |
Per milligram, the 10 mg TB-500 vial works out to $6.00 against $7.00 for the 5 mg vial. The product picks above read the live catalog, so they will show any price change before this table does.
When you compare prices between suppliers, compare like with like. A cheaper vial with no batch-matched lab report is a different purchase from a tested one, because you cannot tell what is in it. If you are weighing a blend against two single vials, peptide blends vs single vials covers the trade-off.
Is TB-500 available in Canada?
Yes. TB-500 is sold in Canada as a research chemical for laboratory use, and pepuro ships it as a lyophilized powder from within the country, so there is no customs hold or import fee at the door.
What Canadian rules restrict is marketing, selling or using a peptide as a drug for human consumption. The line is intended use, not the molecule itself. A research vial of TB-500 carries no Health Canada approval, and a supplier that describes anything beyond the molecule, its handling and its testing is selling it as something it is not. Are research peptides legal in Canada? covers that distinction in full. This page is general information, not legal advice.
How to check a TB-500 vial
Since the name tells you so little, the lab report does the identifying. For TB-500, look for:
- an observed mass near 4963.44 g/mol
- purity at 99% or higher by HPLC
- a batch number that matches the code on the vial
- a named, independent lab
The same checks apply to the blend, where the report also states the ratio for that batch. BPC-157 in Canada runs through them for the other half of the pair.
Every TB-500 vial from pepuro ships free from our Calgary, Toronto and Vancouver distribution centers, dispatched the same business day your e-Transfer clears, with a QR code on the vial that opens its independent, third-party lab report.
For research use only. Not for human or animal consumption.
Frequently asked questions
What does TB-500 stand for?
+
The TB stands for thymosin beta, from thymosin beta-4, the 43-residue peptide TB-500 is based on. The 500 is part of the product name and does not describe the molecule: it is not a residue count, a mass or a vial size.
Is TB-500 the same as TB4?
+
TB4 is shorthand for thymosin beta-4, the natural peptide. TB-500 is the synthetic research peptide based on its active region, supplied in acetylated form. The two names are often used together, which is why the catalog lists it as TB-500 (TB4).
What does TB-500 cost in Canada?
+
At pepuro, a 5 mg vial of TB-500 is $34.99 and a 10 mg vial is $59.99, with free shipping inside Canada. The BPC-157 + TB-500 blend starts at $64.99 for 5 mg of each. The product pages always show the current price.
Is TB-500 available in Canada?
+
Yes, as a research chemical for laboratory use. Canadian suppliers sell it as a lyophilized powder, and pepuro ships 5 mg and 10 mg vials from within Canada. It is not sold as a drug, and a research vial carries no Health Canada approval.
Is TB-500 fragment 17-23 the same thing?
+
No. The fragment is seven residues (LKKTETQ) taken from inside thymosin beta-4, at 729.83 g/mol against 4963.44 g/mol for TB-500. It is a separate product with its own mass-spec target.
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